Not known Facts About phenobarbital sodium injection dailymed
Not known Facts About phenobarbital sodium injection dailymed
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pentobarbital will lower the extent or effect of ziprasidone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.
pentobarbital will minimize the extent or effect of vinorelbine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
pentobarbital will lower the extent or effect of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of. For clients getting exemestane with a powerful CYP3A4 inducer the recommended dose of exemestane is fifty mg day by day after a meal.
pentobarbital will decrease the extent or effect of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unfamiliar.
pentobarbital will lessen the extent or effect of stiripentol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. If struggling to steer clear of coadministration of stiripentol with potent CYP3A4 inducers, maximize stiripentol dose.
pentobarbital will decrease the extent or effect of ondansetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. No dosage adjustment for ondansetron is usually recommended for clients on these drugs.
Unique client inhabitants: Dosage ought to be diminished in the elderly or debilitated because these sufferers may be a lot more sensitive to barbiturates. Dosage really should be reduced for people with impaired renal function or hepatic illness.
pentobarbital will lessen the level or effect of isavuconazonium sulfate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will minimize the level or effect of itraconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.
pentobarbital will lessen the extent or click here effect of vincristine liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unidentified.
Sodium valproate and valproic acid show up to decrease barbiturate metabolism; for that reason, barbiturate blood levels must be monitored and appropriate dosage adjustments manufactured as indicated.
pentobarbital boosts effects of ifosfamide by affecting hepatic enzyme CYP2B6 metabolism. Use Warning/Keep an eye on. Coadministration of ifosfamide with CYP2B6 inducers might increase metabolism of ifosfamide to its metabolite. Observe for greater effects/toxicities if mixed with CYP2B6 inducers.
pentobarbital will lessen the extent or effect of ixabepilone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the level or effect of capivasertib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Potent or average CYP3A inducers lower capivasertib exposure, which can lower efficacy.